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Personalized Precision Immunotherapy Tested in Brain Tumors


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Personalized Precision Immunotherapy Tested in Brain Tumors

In a pilot study in humans, 10 patients with highly malignant glioblastoma brain tumors received a treatment regimen called CAR T cell therapy that reengineers people's own immune cells to recognize cancer-specific proteins. The findings, published July 19 in Science Translational Medicine, could eventually expand the use of CAR T cell-based regimens beyond blood-based cancers like leukemia to solid tumors. "I am firmly convinced that CAR T cells and other immunotherapies have a chance to be a major breakthrough for glioblastoma," said Donald O'Rourke, a professor of neurosurgery at the University of Pennsylvania Perelman School of Medicine and first author on the paper.


By AAAS, USA.


Technology Policy Resource.

Noninvasive Imaging Gets to the Heart of Cardiac Disease Risk


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Noninvasive Imaging Gets to the Heart of Cardiac Disease Risk

A new method of analyzing images from routine heart scans can identify patients most at risk for cardiovascular diseases such as heart attack and stroke, and the method may help doctors deploy therapeutic interventions earlier and more effectively. The approach, described in the 12 July issue of Science Translational Medicine, noninvasively measures blood vessel inflammation as an early warning signal for artery plaques that might go on to rupture and cause major cardiac events.


By AAAS, USA.


Technology Policy Resource.