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Genes, context and ADHD


Genes, context and ADHD

Research published in The Lancet linking Attention Deficit Hyperactivity Disorder (ADHD) to genetic variation provoked widespread media coverage (writes Egenis researcher Ginny Russell). The researchers from the University of Cardiff compared the DNA of 366 children with symptoms of attention deficit hyperactivity disorder and 1,047 control subjects not known to have the condition. They found that 14 per cent of children with ADHD had large, rare variations in their DNA that were present in only 7 per cent of controls. This case-control study looked at whether large deletions and duplications within DNA (called copy number variants or CNVs) might be more common in people with ADHD. Rare CNVs have been found to be associated with conditions such as autism, intellectual disability and schizophrenia, so the researchers wanted to determine whether they might also be associated with ADHD. They were particularly interested in whether ADHD, autism and schizophrenia might all be linked to specific CNVs. .

By E Genis, UK.

Health Policy Resource.